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March 12, 1997                     NEW INFORMATION FROM ACTIS The AIDS Clinical Trials Information Service (ACTIS) is a central resource providing current information on federally and privately sponsored clinical trials for AIDS patients and others infected with HIV.  This service is a Public Health Service project produced collaboratively by the Centers for Disease Control and Prevention, the Food and Drug Administration, the National Institute of Allergy and Infectious Diseases, and the National Library of Medicine.  NAC ONLINE, the computerized information service of the CDC National AIDS Clearinghouse, will alert you to any new information collected by ACTIS. A de_script_ion of a recent clinical trial added to the ACTIS data_base_ is provided below. For more information, call the ACTIS toll-free number to talk with a health specialist.  On request, you can also obtain a printout of a customized search of the clinical trials data_base_s. The information can also be accessed directly by subscribers through two online data_base_s, AIDSTRIALS and AIDSDRUGS, available through the National Library of Medicine.                AIDS CLINICAL TRIALS INFORMATION SERVICE                             1-800-TRIALS-A                            (1-800-874-2572)                           FAX: 1-301-738-6616                         TTY/TDD: 1-800-243-7012                   International Line: 1-301-217-0023 *****************************************************************   PROTOCOL NUMBER:  NIAID ACTG 301.   _title_:  A Phase II, Randomized, Double Blind, Placebo           Controlled Trial of Memantine for AIDS Dementia Complex           (ADC) As Concurrent Treatment with Antiretroviral           Therapy.   PHASE:  Phase II.   DISEASE STATUS:           Patients must have the following symptoms and           conditions:           1. HIV infection, as documented by any licensed ELISA           test kit and confirmed by either Western blot, HIV           culture, HIV antigen, plama HIV RNA or a second           antibody test by a method other than ELISA at any time           prior to study entry.           2. A diagnosis of AIDS dementia complex.                            PATIENT INCLUSION CRITERIA